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A DNA database or DNA databank is a database of DNA profiles which can be used in the analysis of genetic diseases, genetic fingerprinting for criminology, or genetic genealogy.

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The most important function of the forensic database is to produce matches between the suspected individual and crime scene bio-markers, and then provides evidence to support criminal investigations, and also leads to identify potential suspects in the criminal investigation.

When a match is made from a national DNA database to link a crime scene to a person whose DNA profile is stored on a database, that link is often referred to as a cold hit.

A cold hit is of particular value in linking a specific person to a crime scene, but is of less evidential value than a DNA match made without the use of a DNA database.

The first national DNA database in the United Kingdom was established in April 1995, called National DNA Database (NDNAD).

By 2006, it contained 2.7 million DNA profiles (about 5.2% of the UK population), as well as other information from individuals and crime scenes.

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